Stephen Nover's CFB Saturday Bookie Destroyer
(NCAAF) Iowa State vs. Oklahoma, 11/20/2021 12:00 PM, Score: 21 - 28
Point Spread: -3.50 | -106.00 Oklahoma (Home)
Result: Win
Oklahoma has lost just once in November during the last seven years. That lone defeat occurred against Baylor last Saturday.

I'm expecting the Sooners to bounce back in a big way at home against Iowa State, which is 1-3 SU and ATS in its last four road contests.

The Sooners are in must-win mode if they hope to have any chance of making the College Football Playoffs. The 9-1 Sooners also need a victory to realistically keep alive their hopes of capturing a seventh straight Big 12 title.

Iowa State is enduring a disappointing season. The Cyclones are 6-4 and off a 41-38 loss to Texas Tech as a 13-point road favorite.