8* Oklahoma State (3:30 ET): As the only Big 12 team w/o a loss, #6 OK State is probably the conference’s lone chance of sending a team to the CFP. #17 Iowa State is also unbeaten in conference play, but suffered a loss to Louisiana in the season opener that now looks worse than it did a month ago. I’m a little surprised that in Stillwater this line is so low. Favorites have generally struggled ATS this year in College Football, but have covered 10 of the 11 matchups of Top 25 teams so far. Furthermore, chalk of 4 pts or less have gone 20-9 ATS including 9-2 as the home team. Lay the short number in this one.

The reason Iowa State is getting so much respect here probably has to do with the fact HC Matt Campbell has been tremendous in his career as a dog (32-14 ATS) and is 5-0 ATS vs. Top 10 opponents. But the Cyclones easily could be 1-3 SU instead of 3-1 right now. Not only did they lose outright (as a 13-pt home favorite) to Louisiana, but they were outgained at TCU (won 37-34) and trailed by double digits against Oklahoma. Really, the only “complete” performance we’ve seen from ISU was the 31-15 win over Texas Tech two weeks ago, but that’s a team still winless in Big 12 play. This will - easily - be the best defense that will have faced to date.

Oklahoma State has been off for three weeks (COVID-19 related, obviously), which has allowed for QB Spencer Sanders to get healthy. Sanders was injured early in the first game vs. Tulsa and the offense has certainly suffered in his absence. Yet the Pokes are still 3-0. They’ll only get better with Sanders back in the mix. The defense has allowed just 27 points in three games and is #1 in the country on third down, allowing only a 17% conversion rate. The Cowboys have won 7 of the last 8 meetings (including 34-27 LY as a 10-pt dog in Ames) and are 5-3 ATS. 8* Oklahoma State