NCAAF - A lot of points to lay but, per the simulation report, this one has home blowout written all over it. Syracuse is averaging only 264 yards per game but allowing a whopping 464 yards per game this season. The Orange had one tight loss this season but it was against Boston College and the Eagles clearly had their big game with Notre Dame on their mind. Other than that defeat, the other 6 losses for Syracuse have been by an average margin of defeat of 20 points. Louisville's only two wins this season have come at home and the average margin of victory was 23 points per game. The Cardinals offense is averaging nearly 200 yards more per game than the Orange offense this season. Also, the last two meetings between these teams have been won by the home team by an average margin of 26.5 points. Expect this home blowout to be in a similar range per the simulation report. Play LOUISVILLE