The Titans took a 10-0 lead into halftime, and towards the end of the 3rd quarter were driving deep in Vikings' territory up 10-6 at the time. A terrible decision by Mariota led to a 77-yard INT for a TD by the Vikings and another defensive TD on a fumble two drives later pretty much sealed the game for the visitors.
Tenn should be able to move the ball against the Lions defense.

But let's not forget that the Titans looked pretty good for most of the game. Detroit is coming off a road win where they were involved in a shoot-out with the Colts. Indy D is horrible, and I don't think it'll be as easy against the Titans. One major issue for the Lions is that Levy is doubtful, and he's their best linebacker. Against a Titans team that wants to run the ball, Detroit is going to be at a huge disadvantage in the middle level of their D.
I actually expect a close game here and taking the underdog Titans here on Sunday.