I don't have faith in anything the Giants have to offer in this match-up offensively without Saquon and especially defensively. Giants are allowing an average of 34 points per game so far, and giving up 28 to Josh Dobbs and the Cardinals last week (along with an insane comeback) doesn't give me faith they can overcome a much larger mountain from the same division as Arizona. This won't be a massacre like game 1 vs Dallas, but the points will be limited to say the least on this Giants defense, as I expect them to get nothing on the ground outside of some scrambles from Daniel Jones, and forcing them to be one dimensional is what the 49ers will gladly take advantage of in a pass defense that has been underwhelming so far but this will be a great get right game for the Cali DBs. I'm taking the points with the 49ers on a short week where the away team has to quickly figure out what to do without their best player.

Official Play: 49ers -10

Side Bet: Brock Purdy over 1.5 passing TDs

Hail Mary: George Kittle Anytime TD (+175)