Bosa should be in the lineup which will be a boost for the Bolts who are only allowing opponents less than 13 points per game. Murray is going to have to scramble and use his legs if he wants to get any points up on this defense. The Bolts have the better coach and they should get the better of the Cardinals who are 0-4 ATS outside of their division. The Chargers are 2-10 ATS when playing on Monday night since 1993. Arizona is 0-2 ATS when playing on Monday night in the last two seasons. Arizona is 6-13 ATS against AFC West division opponents.

Best bet: take the Chargers on the moneyline (ML).