I'm not in the habit of laying a monster price in baseball. That's especially so this season. But if ever there looked to be a kill spot, this game is it. So I'm not going to pass. I'll get involved laying 1 1/2 runs with the Dodgers on the run line and greatly reduce the vigorish. 
The Dodgers could be the best team in baseball while the Giants just might be the worst. The Giants' already unimposing lineup will be minus Buster Posey, Brandon Belt and Evan Longoria when it faces southpaw Clayton Kershaw. Hunter Pence has a foot injury and might be out, too. San Francisco is 3-8 in its last 11 games versus a lefty starter. 
Kershaw didn't allow an earned run during two spring training starts spanning 4 2/3 innings. Kershaw was 10-2 with a 2.89 ERA at Dodger Stadium last year. He had a 2.37 ERA in four appearances versus the Giants last season. 
Johnny Cueto is slated to start for San Francisco. He figures to be rusty and probably won't pitch for too long being on the comeback trail after pitching in only four games last season while rehabbing from Tommy John surgery. The Dodgers faced Cueto last September rocking him for five runs on five hits, including three homers, in two innings. Cueto won't have any chemistry with whomever backup the Giants elect to go with as their catcher. 
The Giants also have an untested relief corps having lost much of their proven bullen strength. The Dodgers' stacked lineup, bolstered by the addition of Mookie Betts, should have little difficulty taking advantage.