Jon Lester was bit by the long ball bug in his last two starts surrendering a combined six homers to the White Sox and Brewers in his last two starts. 
I see Lester getting his act together facing the woeful Tigers while also being helped by the spacious dimensions of Comerica Park. Lester opened the season giving up just two runs during his first three starts.
Lester is a medium-sized favorite because he's facing Michael Fulmer and a Detroit team that has lost 62 of its last 80 home games.
The Tigers are letting Fulmer take his lumps as he recovers from Tommy John surgery having missed all of last season. Fulmer has given up 18 hits and 14 runs in 11 1/3 innings. That translates into a 9.53 ERA. He has yet to pitch more than three innings in a game this season.