The left side of the Chargers' offensive line consisting of tackle Sam Tevi and guard Forrest Lamp is one of the worst in the NFL. Now, coupled with starting center Mike Pouncey and the right side of the offensive line with guard Trai Turner and tackle Bryan Bulaga being out, I have to lay the touchdown with the Buccaneers.
Tampa Bay's Todd Bowles is one of the better defensive coordinators in the NFL. He has a lot to work with here. The Buccaneers are a top run-stop unit and they're likely to get a lot of sacks against pocket passer rookie Justin Herbert. 
The Buccaneers' offense should improve as the season progresses. It has enough weapons for Tom Brady to safely put up enough points to cover this number. The Chargers have a couple of key defensive injuries and are traveling cross country. An early start time for them certainly is not a plus either.