I have to believe Gregg Popovich is going to have the Spurs ultra competitive in this spot after San Antonio lost two straight to the Grizzlies, both at home. The Spurs' 133-102 loss to Memphis this past Monday was their most lopsided of the season. 
Minnesota is 2-8 in its last 10 games. The Timberwolves' lone victories during this span were against the short-handed Cavaliers and Pelicans. Minnesota has lost eight consecutive road games. 
Karl-Anthony Towns has missed the past nine games. The Timberwolves rarely have been competitive without him. Minnesota has lost by 12 or more points during four of its last five defeats. 
The Spurs aren't going to have LeMarcus Aldridge. I'm fine with that. Aldridge isn't the All-Star of past seasons. The absence of Aldridge is more than offset with the Timberwolves again being without Towns and guard Jarret Culver, a key member of their rotation. 
The Timberwolves are in action for the fourth time in six days. San Antonio won't play again until Saturday against the Rockets in Houston. Another reason the Spurs shouldn't be holding anything back. 
Before losing two in a row to the Grizzlies, the Spurs had defeated the Celtics and Nuggets in their previous home games. So the Spurs are capable of dispatching the Timberwolves by double-digits.