The San Francisco 49ers are 2-0 (defeating Houston and Chicago) since QB Jimmy Garoppolo took over under center, but I don't think they should be favored here against a Tennessee Titans team still in control of its own destiny in the AFC South.

The Titans trail Jacksonville by one game, but they took down the Jags earlier this season and will host them again in Week 17. They need a win here bad though after losing 12-7 at Arizona last week, and we can note that the Titans are 7-3 ATS in their last 10 games following a straight up loss.

My selection is an 8* play on Tennessee Titans.