The San Francisco 49ers have hit a bit of a slump, coming off back-to-back road losses at Cleveland and Minnesota. QB Brock Purdy is doubtful and missed practice on Wednesday while in the NFL's concussion protocol. There's a significant drop off to backup QB Sam Darnold, and here the Niners will face a Bengals team that is coming off its bye week and has played a lot better as Joe Burrows is getting close to full health. I have the Niners as the better team, but the spot favors Cincy, and we're spotted more than a field goal.

5* PLAY ON CINCINNATI BENGALS.