The Arizona Diamondbacks will be in San Diego tonight to play Game 1 of a three game set versus the Padres, and Arizona has won 4-of-7 on this road trip so far. The Padres have a losing record at home for the season, and I don't like their chances against a hot pitcher in the series opener at PETCO.

Here are my keys to the game:

1. Pitching - Rubby De La Rosa will get the call for the visiting D'Backs, and he's been strong in the second half. De La Rosa (13-8, 4.60 ERA) tossed 5.2 scoreless innings in a 2-0 win at San Francisco in his last start. He's 7-1 with a 3.88 ERA in his last 12 starts. The Padres will counter with rookie right-hander Casey Kelly, who is making his season debut. He allowed one run on five hits in two innings of relief a few days ago.

2. Paul Goldschmidt - The Arizona slugger continues to swing a hot bat, hitting .385 with three home runs over the last seven days. He's hitting .304 with a home run and five RBIs at PETCO this year.

3. X-Factor - The Diamondbacks are 21-8 in their last 29 road games vs. a team with a losing home record.

Selection: This is a play on the Arizona Diamondbacks (10*)