The set-up: The Cards and Seahawks met in Week 7 at Phoenix with the game ending in a 6-6 overtime time. These two NFC West rivals meet again here in Week 16 but only the Seahawks have something to play for. The Cards, who went 13-3 in last year's regular season and made the NFC championship game, enter this contest just 5-8-1 and have nothing to play for but pride and the hope of playing spoiler. As for Seattle, the Seahawks are 9-4-1 and own a half-game lead over the 9-5 Detroit Lions for the NFC's No. 2 seed, which comes with a first round bye.

Arizona: The first meeting between the two teams was like a heavyweight championship fight and asked about the game Arizona QB Carson Palmer said "It was a great game. I know a lot of people thought it wasn't, but it was a battle, an NFC West battle. They played really well, we played really well and it came out as a draw obviously. They're not going to change a ton, I assume. They do what they do very well, and they don't change a ton for good reason." Unfortunately for the Cards, they are not nearly as strong as they were two months ago, as injuries have left them decimated at several positions. Both starting tackles are out, they no longer have WR Michael Floyd, they lost starting LB Deone Bucannon to a season-ending ankle injury and safety Tyvon Branch to another groin injury. Safety Tyrann Mathieu still isn't close to 100 percent, either, and it's shown on the field after the "Honey Badger" returned from missing four games during a five-game stretch. Coming off a career year in 2015, Palmer has looked very ‘old' in 2016. He's got 22 TDs and 13 INTs with a QB rating of 85.8, after throwing for a career-high 35 TD passes last year (with just 11 INTs), while earning a QB rating of 104.6, which was also a career best. The bright spot in an otherwise down campaign for Arizona has been RB David Johnson, who set an NFL record with 14 straight games of 100 or more yards from scrimmage to start the season and was named to his first Pro Bowl this week. Johnson leads the league in yards from scrimmage with 1,938 and has scored 17 touchdowns so far, piled up 113 rushing yards and caught eight passes for 58 yards in the first meeting with Seattle. "There is nobody better than he is," wide receiver Larry Fitzgerald (98 catches but just 9.7 YPC with only 5 TDs), who will make his 10th Pro Bowl appearance, told reporters of Johnson. "He's playing at the highest level. He does it in the run game, the pass game, great pass protector as well. The guy can do it all. It's a real joy and a pleasure to be able to watch a guy do something like that and be his teammate."

Seattle: The tie at Arizona was one of several examples this season of Seattle's offense stalling in road games and the club followed up a 38-10 loss at Green Bay in Week 14 with a 24-3 home triumph over Los Angeles last week that clinched the NFC West crown. Seattle is 7-0 at home but 2-4-1 on the road. The team's 7-0 home mark this year makes Russell Wilson 34-5 SU at home as a starter and the Arizona defense he faces this Saturday is not the same one he saw back in Week 7's 6-6 tie (more on that in a bit). Seattle was allowing the fewest points of any team until the Packers scored 38 on them in Week 14 and with two games left, Seattle still has a chance to catch the Pats, who have allowed just two fewer points on the year, 233 to 235. Seattle has led the league in points allowed the last four seasons and no team has ever done it in five straight seasons.

The pick: Wilson's home record speaks for itself and the Arizona defense he'll see on Saturday in no way resembles the unit he faced back at Phoenix in Week 7. The Cardinals have fallen apart defensively since that game, allowing an average of 30.7 PPG while going 2-5 SU and 1-6 ATS. Seattle should score plenty and as we saw last week against the Saints, the Cards are still more than capable offensively. The Over is a 10* play.