The Astros are just 1-4 in their last five home games against left-handed starters and their lineup is hitting just .216 against Seattle starter James Paxton. I like Seattle in this matchup on Wednesday afternoon. The Mariners are also 5-1 when Paxton faces winning teams, and are 7-2 when he starts Game 3 of a series. Look for Seattle and Paxton to keep the Astros in check in this one.