I am backing Wade Miley and the Arizona Diamondbacks here. Miley comes into this start after coming off of a very good spring training where he posted a 2.41 era through 18 innings with 4 BBs, 13 Ks while allowing 0 HRs. When we look at Miley's first outings from 2012 & 2013, we can see that he looks to get the season off on the right foot where he allowed just 1 run through 10 innings on 8 Ks.
The Giants have a combined 110 ABs off of Miley but with little success as they hit .273 with just 1 HR off of Miley. Matt Cain, on the other hand, did not show much success during his spring training as he posted a 7.47 era through 15 innings on 6 BBs, 13 Ks and 2 HRs. When we look at Cains first starts of the 2012 & 2013 season, Cain allowed 5 runs through 12 innings on 10 hits, 2 BBs & 2 HRs. With the Diamondbacks having already faced three aces in Clayton Kershaw, Bumgarner and Ryu, I like Arizona in this spot Tuesday night.