This is an open match between two lower seeded teams, and I think edge here is with The Foxes. The leadership in the front with Vardy and the depth that Leicester have will overpower the revamped side of Southampton, who will look to take a defensive approach to this matchup. Brendan Rogers needs this win to spark confidence in his team's outlook for the season, and after putting 2 goals on Arsenal in a loss, the team has to be assured that this is a very winnable game.

Official Play: Leicester -0.75

Side Bet: Under 2.5 Goals