Play - San Francisco 49ers (Game 425).

> Edges for the 49ers:
• QB Brock Purdy 8-1 SU and 7-2 ATS versus foes with a winning record, including 6-0 SUATS in games when San Francisco owns a .777 or fewer win percentage
• 4-0 ATS versus NFC East in the last three regular seasons
• 5-1 ATS versus .750 or greater opponents

> Edges against the Eagles:
• 4-7-1 ATS at home off a home win in which they scored more than 36 points, including 0-3 SUATS if they were not favored by 6 or more points in their last game
• Beat San Francisco in last year’s NFC championship game in which QB Brock Purdy was injured early and had to leave the game

> Conclusion:
• Our Well-Oiled Machine seals the deal by noting that NFL teams on a three-game win streak exact that was preceded by a Bye week are 18-7-1 ATS, including 8-0 ATS since 2014. With the Eagles 4-0 SU last four games but outgained by 127, 98, 114, and 98 yards - or an average of -113 net yards - in those contests, we recommend a strong 4* play on San Francisco as our NFL Game of the Week. We wish you the best of luck and thank you for your continuing support.

> With six winners in the last seven weeks, you don’t want to make a play on Sunday's NFL card when you learn of a live dog supported with a 100% perfect system since 1990 - winning every game outright. It comes directly from Marc's NFL Perfect System Club, and it's locked and loaded - get it now!

**Selection ratings:
1* free play,
2* quality opinion play,
3* top quality selection,
4* top quality strong selection,
5* top quality exceptional selection,
10* top quality, highest-rated choice.
Note: Most top selections appear on Marc's Preferred Picks Executive LTS Service.