Stephen Nover's NFL Blockbuster - 17-2-2 (89%) Run!
(NFL) Indianapolis vs. Tennessee,
Point Spread: -3.00 | -116.00 Indianapolis (Away)
Result: Win
The Colts knocked out Marcus Mariota when they played the Titans in Week 11. The Colts buried the Titans, 38-10, in that game. Andrew Luck torched the Titans for 297 yards passing and three touchdowns. Luck is 10-0 lifetime versus Tennessee.

Luck is an elite quarterback and now, for the first time, has an elite pass-blocking offensive line. The Colts are very underrated defensively giving up the 11th fewest yards and 13th fewest points.

I expect Mariota to start for the Titans. But he's not likely 100 percent and he's not that good even when he is healthy unable to consistenly hurt a defense with downfield throws.

The Titans' strategy has become feed Derrick Henry and rely on a good - but not great - defense. The Colts rank eighth in run defense. They are going to stack the line keying on Henry. Then what for the Titans? I don't see them being able to keep up with Luck, who is back to elite status and has found a decent running back in Marlon Mack.

If the Colts are able to build a big early lead the Titans are in real trouble because that would take Henry out of the mix.

The Colts have been playing extremely well going 8-1 in their last nine games, charging hard for a playoff spot. I believe they are the better team with the much superior quarterback. The Titans' home field is strong, but not strong enough to compensate for them being the weaker foe.