The Cubs and their starting pitcher, Kyle Hendricks, play much worse on the road. Chicago is 13 games below .500 away from Wrigly Field. Hendricks has a 1.77 ERA and 0.77 WHIP at home, but is 4-7 on the road with a 5.20 ERA and 1.44 WHIP. The Cubs have lost six of Hendrick's last eight away starts. 
San Diego starter Cal Quantrill isn't in good form. However, he shut out the Cubs on two hits in 5 2/3 innings when he last faced them on July 21. Quantrill struck out six and did not walk a batter. Hendricks started that game for the Cubs. San Diego won, 5-1. 
The Cubs could be down four key players. Star shortstop Javier Baez and closer Craig Kimbrel are both out. Infielder Addison Russell isn't likely to play either after getting hit in the head with a pitch yesterday. Kris Bryant missed Sunday's game with a sore knee. So he's questionable.