Tampa Bay can pass the ball effectively and stop the run. Those are two key components when taking on the Seahawks. Seattle is heavily run-oriented. The Buccaneers give up just 68.6 yards rushing, best in the NFL. Tampa Bay's pass rush is upgraded, too, with the return of Jason Pierre-Paul. He'll team up with NFC sacks leader Shaq Barrett. 
Jameis Winston has strong receiving weapons. Seattle ranks 27th in pass defense and has injuries with safeties Tedric Thompson and newly acquired Quandre Diggs out. The Seahawks have only three sacks in their past four games. 
The Buccaneers have proven dangerous as road 'dogs already knocking off the Panthers and Rams. Seattle has failed to cover the past four times it has been a home favorite, including nearly losing to the Bengals and falling by 14 points to the Ravens two games ago.