The Chargers are a level higher than the Raiders. Injuries and Melvin Gordon's holdout held the Chargers back earlier in the season. But now they have gotten healthier and just played their most complete game in rolling over the then 7-1 Packers by 15 points this past Sunday. Look for that strong play to carry into this game.
Gordon looked great against the Packers. Hunter Henry is back giving Philip Rivers a top-notch tight end receiving target. The Chargers' play-calling and tempo was much crisper, too, in Shane Steichen's first game as offensive coordinator. 
Rivers has averaged 304.2 yards with an 8-to-1 touchdown-to-interception ratio in his last four games against the Raiders. Oakland ranks last in pass defense and just lost one of its few decent pass rushers in Arden Key. 
Joey Bosa is the best defensive plater on the field. He could cause a lot of havoc for Derek Carr, who could be missing starting offensive right tackle Trent Brown and center Rodney Hudson. Carr isn't nearly as effective under a heavy pass rush as other quarterbacks. 
The Chargers have won the covered the past four in the series, including winning by an average of 15 points in the two games last season.