If you go by the highly respected KenPom.com ratings you'll see that Cincinnati is ranked 63rd and Furman right behind the Bearcats at 64. 
The Paladins are favored to win the Southern Conference. They have played only low-major opponents so far, but the results have been impressive: 4-0 with an average victory margin of 31.2 points. Furman had one of the 100 most efficient offenses in the country last season. The Paladins were among the top 10 best mid-majors in the country. 
So this isn't going to be an easy opponent for Cincinnati, especially given that the 1-1 Bearcats aren't playing well defensively and don't have a set rotation.
This quote from Cincinnati coach John Brannen is telling: "I'm really learning our team," Brannen said following the Bearcats' 77-69 loss to Xavier this past Sunday. "We don't have a rotation yet. Those are things that we're learning." 
Furman guard Mike Bothwell is playing at a very high level averaging nearly 22 points a game. The Paladins have covered five of their last six road games. 
The Bearcats are 0-7 ATS at home going back to last season and 1-6 ATS after not covering in their previous game.