Buffalo has lost some talent, but the Bulls still will have the two best players on the court in Jeenathan Williams and Jayvon Graves. They've combined to average 37 points and 16 rebounds per game. 
I see the Bulls having too much firepower for Miami of Ohio. The Bulls are tough on the glass and they outscore the RedHawks by eight points per game. 
Buffalo has major revenge, too, after the RedHawks upset them as 9-point 'dogs in the first round of the Mid-American Conference Tournament last season.