This is a bad matchup for Tulane. The Green Wave of New Orleans are making a long journey into cold weather where the temperature is going to be in the 20's and the winds will be flapping at 15-25 mph. 
Nevada is well familiar with the special blue turf and field conditions in Boise State's home stadium, site of the Potato Bowl. 
The Wolf Pack have a monster passing edge with Carson Strong, the best quarterback in the Mountain West Conference. He led the conference in completions, completion percentage, TD's and passing yards. Strong has two all-conference receiving targets in wide receiver Romeo Doubs and tight end Cole Turner. The Wolf Pack also have all-conference placekicker Brandon Talton. 
Tulane could be down three starting defensive linemen with two of its starters definitely ruled out. The Green Wave struggled against strong passing opponents. Central Florida put up 51 points on Tulane while Houston scored 49 points on the Green Wave. 
The Green Wave are run-oriented, but that's Nevada's defensive strength. Tulane lost its up-and-coming offensive coordinator, Will Hall. He left to become head coach at Southern Mississippi. 
Tulane's defensive coordinator was fired so the Green Wave are without both of their coordinators.