Maybe the Bulls will be better under their new coach, Billy Donovan. But that time isn't now. Chicago was horrendous in its opening game surrendering 83 points in the first half of a 124-104 home loss to the Hawks. 
The Bulls are brutal as home 'dogs failing to cover 24 of the past 33 times in that role.
Indiana has been very strong as road chalk going 9-1-1 ATS the past 11 times when favored on the road. 
The Pacers have reached the playoffs each of the past four seasons. The Bulls last made the postseason in 2017. 
Nate Bjorkgren had a successful Indiana coaching debut this past Wednesday. The Pacers took care of business with a 121-107 home win against the Knicks. Now Indiana draws another Eastern Conference bottom feeder. I don't see the Bulls doing any better than the Knicks did against the Pacers especially with Victor Oladipo finally appearing fully healthy.