Grand Canyon has been an underdog five times this season. The Antelopes covered every one of those games. Iowa is a great team, but Grand Canyon matches up well to the Hawkeyes and should go 6-0 ATS as an underdog. 
The Hawkeyes are led by star senior center Luka Garza. Grand Canyon has a pair of big men - 7-footer Asbjorn Midtgaard and 6-10 Alessandro Lever - that can bother Garza on both sides of the floor. The Antelopes ranked 16th in the nation in 2-point shooting at 55.4 percent because of their inside scoring. They also were 35th in the nation in offensive rebounding. 
Iowa doesn't have the guard play to force many turnovers, which is where Grand Canyon has some vulnerabilities. 
Making the NCAA Tournament is a huge deal for the Antelopes because they never made it before having just started playing Division I basketball eight years ago. Grand Canyon will be pumped up while all the pressure will be on Iowa. 
You have to wonder, too, if the Big Ten could be overrated following Ohio State and Purdue losing as big favorites during Friday's first-round tournament action.