The Niners have had some serious injury problems, which has caused them to struggle this season.
The Saints are now healthy and took TB to the woodshed last Sunday. Brees has been incredibly efficient this season, from his completion percentage to his 17-to-3 touchdown-to-interception ratio. He has one of the deadliest weapons in the NFL at his disposal in running back Alvin Kamara. It has been a balanced effort for Kamara, who leads the team in rushing and passing. He is averaging 4.9 yards per carry on 96 attempts, picking up 471 yards and five touchdowns. Kamara has also caught 60 passes for 565 yards and three touchdowns.
They have a lot of weapons and should move the ball vs a banged up 49ers secondary.