Major
(NFL) Philadelphia vs. Indianapolis,
Point Spread: 3.00 | 100.00 Philadelphia (Away)
Result: Win
The Indianapolis Colts will be without starting linebacker Jerrell Freeman. They are already missing Robert Mathis. They are struggling on the OL. In fact, in short Indianapolis is very strong at QB and WR and weak everywhere else. Offensive lineman Joe Reitz is also out.

The Eagles have their share of offensive talent and do not have the weaknesses Indianapolis does. Home teams in September in virtual pick (+/- three points of pick) off road loss are 86-132-11. Obviously that applies to the Colts and benefits the Iggles.