San Francisco at Denver 8:30 ET
Broncos (-) over 49ers- After the way the Broncos beat 'us' last week with a pick-six touchdown return on the final play of the game takes a little away from my enthusiasm to come back with Denver but the 49ers comeback against the Rams on Monday night sets this up fine. Peyton Manning with have the stage to set the NFL record for career touchdown passes passing Brett Favre. San Francisco will be without two of their three linebackers but they remain the number 2 defense in passing and total yards. It what could become a 'classic' take DENVER!