Louisville is tough and at home but we've seen them implode with self-inflicted wounds. Look no further than last week against Stanford for proof of that concept. Pitt has been solid most of the year and has hung tough against the best the ACC has had to offer with the exception of the game against SMU when they were trucked. The Panthers, with Holstein or Yarnell under center, can move the ball and Desmond Reid delivers some big plays. Louisville may find a way to win but it's a closer game than anyone may expect.