Indianapolis Colts -2.5
(NFL) Colts (IND) vs. Patriots (NE),
Point Spread: -2.50 | -115.00 Colts (IND) (Away)
Result: Loss
The Patriots have struggled on both sides of the ball this season and things won't get any easier here. Indianapolis has a good run game led by Jonathan Taylor and they still have hopes of making a push for a postseason berth. With Josh Downs sidelined for the Colts, you have to think that Taylor will get plenty of work against a New England defense that is giving up more than 120 yards per game on the ground. If there was a chance for Anthony Richardson to get right for one game this season, this would be it.