Ohio State has a chip on their shoulder and they are not in the national championship conversation. Indiana has been decimated in the transfer portal and don't have a good quaterback nor any defense to speak of. This is a game where Ohio State absolutely rolls over Indiana with all their top talent and skill players, this will not be close at all. When Ohio State plays in Indiana, the Buckeyes are 10-3 against the spread versus Indiana since 1992.

Indiana are 5-13 ATS in their last 18 games against an opponent in the Big Ten conference. Indiana are 2-6 ATS in their last 8 games played in week 1. Indiana are 0-11 SU in their last 11 games when playing at home against Ohio State. Ohio State are 11-4-1 ATS in their last 16 games played in week 1. Indiana are 4-14 ATS as an underdog.

Best bet: lay the points with Ohio State.