Yusei Kikuchi is 2-4 with an ERA of 9.12 in 12 career appearances vs. LA. He allowed nine runs on 12 hits (four HRs) in his last two starts against the Angels (11.1 IP). Mickey Moniak, Logan O'Hoppe and Taylor Ward have all taken him yard in 16 combined ABs.

The Angels bounced back from their six-game winning streak with consecutive wins in their last two games. The Astros dropped two of three to the Padres in San Diego in a tough series that ended Wednesday.

LA sports a 38-31 run line record as road underdogs, while Houston is 30-36 against the run line as home favorites this year.